Alfacalcidol
Brands: One-Alpha, Alfacalcidol Teva
Alfacalcidol is a vitamin D analog used for calcium regulation in pets.
Used for
- Hypocalcemia
- Renal osteodystrophy
- Hyperparathyroidism
How it is given
- Administration
- oral
- Frequency
- once daily
- Duration
- as prescribed by a veterinarian
- Storage
- Store in a cool, dry place away from direct sunlight.
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- 0.05-0.1 mcg/kg once daily
dog
- Large dogs
- 0.1-0.2 mcg/kg once daily
- Small dogs
- 0.02-0.05 mcg/kg once daily
- Medium dogs
- 0.05-0.1 mcg/kg once daily
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- Alfacalcidol
Side effects
Common
- Increased thirst
- Increased urination
Rare
- Vomiting
Severe
- Hypercalcemia requiring vet attention
Do not use when
- Hypercalcemia
- Hypersensitivity to vitamin D
Interacts with
- Corticosteroids
- Thiazide diuretics
Warnings
- Monitor calcium levels regularly
- Use with caution in hyperphosphatemia
Alfacalcidol questions
How does Alfacalcidol differ from regular vitamin D?
Alfacalcidol is a precursor to active vitamin D, allowing for easier regulation of calcium without the need for kidney conversion.
Can Alfacalcidol be used in pregnant pets?
Use with caution and only under veterinary supervision due to potential risks to the fetus.
How long does it take to see improvements?
Effects can be seen within a few weeks, but regular monitoring is essential.
Can Alfacalcidol be given with food?
Yes, it can be administered with or without food.
What should I do if a dose is missed?
Administer as soon as possible unless it's close to the next dose. Do not double the dose.
Full drug detail
Overview
Alfacalcidol is a vitamin D analog used to manage calcium levels in pets, particularly in cases of renal insufficiency or hypocalcemia. It helps in the synthesis of active vitamin D, aiding calcium absorption and bone health.
How It Works
Alfacalcidol is metabolized in the liver to calcitriol, the active form of vitamin D. This enhances intestinal absorption of calcium and phosphate, promoting bone mineralization and managing parathyroid hormone levels.
Uses & Indications
Alfacalcidol is primarily used to treat:
- Hypocalcemia
- Renal osteodystrophy
- Hyperparathyroidism
Dosage Guidelines
Consult a veterinarian for precise dosing, as it can vary based on the animal's condition and response.
Dogs
- Small Dogs: 0.02-0.05 mcg/kg once daily
- Medium Dogs: 0.05-0.1 mcg/kg once daily
- Large Dogs: 0.1-0.2 mcg/kg once daily
Cats
- Standard: 0.05-0.1 mcg/kg once daily
Administration
Alfacalcidol is administered orally and can be given with or without food.
Side Effects
Common
- Increased thirst
- Increased urination
Rare
- Vomiting
Severe
- Hypercalcemia (requires immediate veterinary attention)
Precautions & Warnings
- Monitor calcium levels regularly to avoid hypercalcemia.
- Use with caution in pets with hyperphosphatemia.
Drug Interactions
- Corticosteroids: May reduce effectiveness
- Thiazide diuretics: Increased risk of hypercalcemia
Storage
Store in a cool, dry place away from direct sunlight.
FAQ
How does Alfacalcidol differ from regular vitamin D?
Alfacalcidol is a precursor to active vitamin D, allowing for easier regulation of calcium without the need for kidney conversion.
Can Alfacalcidol be used in pregnant pets?
Use with caution and only under veterinary supervision due to potential risks to the fetus.
How long does it take to see improvements?
Effects can be seen within a few weeks, but regular monitoring is essential.
Can Alfacalcidol be given with food?
Yes, it can be administered with or without food.
What should I do if a dose is missed?
Administer as soon as possible unless it's close to the next dose. Do not double the dose.