Alfaxalone
Brands: Alfaxan, Alfaxan Multidose
Alfaxalone is a sedative used in veterinary medicine for anesthesia in dogs and cats.
Used for
- induction of anesthesia
- maintenance of anesthesia
- sedation
How it is given
- Administration
- injection
- Frequency
- as needed
- Duration
- short procedures
- Storage
- Store below 25°C, protect from light
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- 5 mg/kg IV
dog
- Large dogs
- 3-4 mg/kg IV
- Small dogs
- 1-2 mg/kg IV
- Medium dogs
- 2-3 mg/kg IV
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- Alfaxalone
Side effects
Common
- hypotension
- respiratory depression
Rare
- excitement during recovery
Severe
- severe respiratory depression requiring vet attention
Do not use when
- cardiovascular disease
- respiratory compromise
Interacts with
- other CNS depressants
- other anesthetics
Warnings
- important to monitor vital signs
- adjust doses for animals with liver issues
Alfaxalone questions
Is Alfaxalone safe for puppies?
Alfaxalone can be used in puppies under veterinary guidance.
Can Alfaxalone be used for long procedures?
It is typically used for short procedures but can be maintained with repeat doses as needed.
What to do if my pet shows severe side effects?
Contact your veterinarian immediately if severe side effects occur.
How long does it take for Alfaxalone to work?
Alfaxalone typically works within minutes when administered intravenously.
Is Alfaxalone a controlled substance?
Alfaxalone is not a controlled substance but requires a prescription.
Full drug detail
Overview
Alfaxalone is a neuroactive steroid anesthetic widely used in veterinary medicine for inducing anesthesia in pets, particularly dogs and cats. It offers a rapid onset and short duration of action, making it a preferred choice for short procedures.
How It Works
Alfaxalone works by enhancing the activity of gamma-aminobutyric acid (GABA) receptors in the brain, leading to sedation and loss of consciousness. This mechanism results in smooth induction and recovery from anesthesia.
Uses & Indications
Alfaxalone is primarily used for:
- Induction of anesthesia
- Maintenance of anesthesia
- Sedation for short, minor procedures
Dosage Guidelines
Dogs
- Small Dogs: 1-2 mg/kg IV
- Medium Dogs: 2-3 mg/kg IV
- Large Dogs: 3-4 mg/kg IV
Cats
- Standard: 5 mg/kg IV
Administration
Alfaxalone is administered via injection and is typically given intravenously for rapid effect.
Side Effects
Common
- Hypotension
- Respiratory depression
Rare
- Excitement during recovery
Severe
- Severe respiratory depression requiring veterinary attention
Precautions & Warnings
- Use with caution in animals with cardiovascular disease.
- Monitor respiratory and cardiovascular function during anesthesia.
Drug Interactions
- May interact with other CNS depressants.
- Use caution when combined with other anesthetics.
Storage
Store below 25°C (77°F) and protect from light. Do not freeze.
FAQ
Is Alfaxalone safe for puppies?
Alfaxalone can be used in puppies under veterinary guidance.
Can Alfaxalone be used for long procedures?
It is typically used for short procedures but can be maintained with repeat doses as needed.
What to do if my pet shows severe side effects?
Contact your veterinarian immediately if severe side effects occur.
How long does it take for Alfaxalone to work?
Alfaxalone typically works within minutes when administered intravenously.
Is Alfaxalone a controlled substance?
Alfaxalone is not a controlled substance but requires a prescription.