Frontline (Fipronil)
Brands: Frontline, Frontline Plus
Frontline is a topical antiparasitic treatment for dogs and cats, effective against fleas and ticks.
Used for
- flea control
- tick control
- lice control
How it is given
- Administration
- topical
- Frequency
- monthly
- Duration
- year-round for ongoing protection
- Storage
- Store at room temperature away from sunlight
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- 0.5 ml
dog
- Large dogs
- 2.68 ml
- Small dogs
- 0.67 ml
- Medium dogs
- 1.34 ml
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- Fipronil
Side effects
Common
- skin irritation
- temporary hair loss
Rare
- vomiting
Severe
- allergic reactions
Do not use when
- hypersensitivity
- under 8 weeks of age
Interacts with
- no significant interactions
Warnings
- do not use on rabbits
- avoid contact with eyes
Frontline (Fipronil) questions
Can I use Frontline on pregnant pets?
Caution is advised; consult a veterinarian.
How soon can I bathe my pet after application?
Wait 48 hours after application to bathe your pet.
What if my pet licks the application site?
Monitor for any adverse reactions and contact a vet if concerned.
How long does Frontline take to work?
Frontline begins killing fleas within 4 hours and ticks within 48 hours.
Is Frontline waterproof?
Yes, Frontline remains effective after bathing and swimming, once absorbed.
Full drug detail
Overview
Frontline, with the active ingredient Fipronil, is a widely used topical treatment to control fleas and ticks in dogs and cats. It offers month-long protection and is known for its efficacy against various external parasites.
How It Works
Fipronil targets the nervous system of fleas and ticks, leading to their death. It disrupts the normal functioning of the gamma-aminobutyric acid (GABA)-gated and glutamate-gated chloride channels in the parasites.
Uses & Indications
Frontline is primarily indicated for the treatment and prevention of flea infestations, tick infestations, and to control chewing lice in pets. It is effective in killing adult fleas, ticks, and lice.
Dosage Guidelines
Dogs
- Small Dogs (5-22 lbs): One pipette of 0.67 ml
- Medium Dogs (23-44 lbs): One pipette of 1.34 ml
- Large Dogs (45-88 lbs): One pipette of 2.68 ml
Cats
- Standard: One pipette of 0.5 ml
Administration
Frontline is applied topically between the shoulder blades of the pet. Ensure the pet's coat is dry before application.
Side Effects
Common
- Mild skin irritation
- Temporary hair loss at application site
Rare
- Vomiting
Severe
- Allergic reactions requiring immediate veterinary attention
Precautions & Warnings
- Avoid using on pets under 8 weeks of age.
- Do not use in pets with known hypersensitivity to Fipronil.
Drug Interactions
- No significant drug interactions are known, though consult a veterinarian if using other topical treatments.
Storage
Store at room temperature, away from direct sunlight and moisture.
FAQ
- Can I use Frontline on pregnant pets? Caution is advised; consult a veterinarian.
- How soon can I bathe my pet after application? Wait 48 hours after application to bathe your pet.
- What if my pet licks the application site? Monitor for any adverse reactions and contact a vet if concerned.
- How long does Frontline take to work? Frontline begins killing fleas within 4 hours and ticks within 48 hours.
- Is Frontline waterproof? Yes, Frontline remains effective after bathing and swimming, once absorbed.