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Ketoconazole

Brands: Nizoral, Ketochlor

Ketoconazole is an antifungal medication used in pets to treat infections. Consult your vet before use.

Prescription requiredimidazole antifungalantifungaldogcat

Used for

  • dermatophytosis
  • blastomycosis
  • histoplasmosis

How it is given

Administration
oral
Frequency
once daily
Duration
weeks to months
Storage
Store in a cool, dry place away from sunlight.
Pregnancy safety
caution

Always confirm the exact dose with your veterinarian before giving any medicine.

Typical dose ranges

cat

Standard
5-10 mg/kg per day

dog

Large dogs
5-10 mg/kg per day
Small dogs
5-10 mg/kg per day
Medium dogs
5-10 mg/kg per day

Ranges are reference only. Your vet sets the dose for your pet's weight and condition.

Active ingredients

  • Ketoconazole

Side effects

Common

  • vomiting
  • diarrhea

Rare

  • liver toxicity

Severe

  • signs of liver failure

Do not use when

  • liver disease
  • hypersensitivity

Interacts with

  • cyclosporine
  • antacids

Warnings

  • monitor liver function
  • avoid in liver disease

Ketoconazole questions

What is Ketoconazole used for in pets?

Ketoconazole is used to treat fungal infections such as ringworm and blastomycosis.

Can Ketoconazole be given with food?

Yes, it can be given with food to reduce stomach upset.

How long does it take for Ketoconazole to work?

Improvements can be seen within a few days, but full treatment duration should be completed.

Is Ketoconazole safe for pregnant pets?

Use with caution and only under veterinary guidance.

Can I stop Ketoconazole if my pet feels better?

Do not stop without consulting your vet, as premature discontinuation can lead to recurrence.

Full drug detail

Overview

Ketoconazole is a widely used antifungal medication in veterinary medicine, primarily for treating fungal infections in dogs and cats. It inhibits the growth of fungi by interfering with their cell membranes.

How It Works

Ketoconazole works by blocking the synthesis of ergosterol, an essential component of fungal cell membranes. This action disrupts cell membrane formation, ultimately leading to the death of the fungal cells.

Uses & Indications

Ketoconazole is used to treat a variety of fungal infections, including:

  • Dermatophytosis (ringworm)
  • Blastomycosis
  • Histoplasmosis Always consult with a veterinarian for a proper diagnosis and treatment plan.

Dosage Guidelines

Dosage should always be determined by a veterinarian.

Dogs

  • Small Dogs: 5-10 mg/kg per day
  • Medium Dogs: 5-10 mg/kg per day
  • Large Dogs: 5-10 mg/kg per day

Cats

  • Standard Dosage: 5-10 mg/kg per day

Administration

Ketoconazole is administered orally in the form of tablets.

Frequency

Typically administered once daily, but follow your veterinarian's instructions.

Duration

The duration of treatment can range from several weeks to months, depending on the severity of the infection.

Side Effects

Common

  • Vomiting
  • Diarrhea

Rare

  • Liver toxicity

Severe

  • Signs of liver failure (yellowing of the skin or eyes) require immediate veterinary attention.

Precautions & Warnings

  • Monitor liver function during treatment.
  • Avoid use in animals with liver disease.

Drug Interactions

  • Cyclosporine: Can increase blood levels of cyclosporine.
  • Antacids: May decrease absorption of ketoconazole.

Storage

Store in a cool, dry place away from direct sunlight.

FAQ

What is Ketoconazole used for in pets?

Ketoconazole is used to treat fungal infections such as ringworm and blastomycosis.

Can Ketoconazole be given with food?

Yes, it can be given with food to reduce stomach upset.

How long does it take for Ketoconazole to work?

Improvements can be seen within a few days, but full treatment duration should be completed.

Is Ketoconazole safe for pregnant pets?

Use with caution and only under veterinary guidance.

Can I stop Ketoconazole if my pet feels better?

Do not stop without consulting your vet, as premature discontinuation can lead to recurrence.

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