Probenecid
Brands: Benemid, Probalan
Probenecid is used to enhance antibiotic effectiveness in dogs. Always consult a vet.
Used for
- enhance antibiotic effectiveness
- bacterial infections
How it is given
- Administration
- oral
- Frequency
- twice daily
- Duration
- determined by vet
- Storage
- Store at room temperature, away from moisture and heat
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- Not commonly used
dog
- Large dogs
- 10 mg/kg
- Small dogs
- 10 mg/kg
- Medium dogs
- 10 mg/kg
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- Probenecid
Side effects
Common
- Gastrointestinal upset
- Nausea
Rare
- Skin rash
Severe
- Severe allergic reactions
Do not use when
- kidney issues
- known hypersensitivity
Interacts with
- Penicillin
- Methotrexate
Warnings
- Not suitable for animals with kidney issues
- Caution in pregnant dogs
Probenecid questions
How does Probenecid work?
Probenecid increases antibiotic levels by reducing their excretion.
Can Probenecid be used in cats?
It is not commonly used in cats; consult your vet.
What should I do if my dog misses a dose?
Give it as soon as you remember, unless it is close to the next dose.
Is Probenecid safe for pregnant dogs?
Use with caution; consult your vet.
Can side effects be severe?
Severe allergic reactions require immediate veterinary attention.
Full drug detail
Overview
Probenecid is a uricosuric agent primarily used to increase the effectiveness of certain antibiotics in dogs. It works by inhibiting the excretion of penicillin and other antibiotics, increasing their levels in the bloodstream.
How It Works
Probenecid functions by blocking renal tubular excretion, thus maintaining higher levels of antibiotics in the blood, which enhances their effectiveness against infections.
Uses & Indications
Probenecid is used in dogs to:
- Enhance the effectiveness of penicillin.
- Treat certain types of bacterial infections.
Dosage Guidelines
Dosage should always be determined by a veterinarian. Typical guidelines are:
- Small Dogs: 10 mg/kg
- Medium Dogs: 10 mg/kg
- Large Dogs: 10 mg/kg
Administration
Probenecid is administered orally.
Frequency
Often administered twice daily.
Duration
Duration is typically determined by the underlying condition and response to treatment.
Side Effects
Common
- Gastrointestinal upset
- Nausea
Rare
- Skin rash
Severe
- Severe allergic reactions (seek immediate veterinary care)
Precautions & Warnings
- Not suitable for animals with kidney issues.
- Use with caution in pregnant or lactating dogs.
Drug Interactions
- Penicillin
- Methotrexate
Storage
Store at room temperature, away from moisture and heat.
FAQ
-
How does Probenecid work? Probenecid increases antibiotic levels by reducing their excretion.
-
Can Probenecid be used in cats? It is not commonly used in cats; consult your vet.
-
What should I do if my dog misses a dose? Give it as soon as you remember, unless it is close to the next dose.
-
Is Probenecid safe for pregnant dogs? Use with caution; consult your vet.
-
Can side effects be severe? Severe allergic reactions require immediate veterinary attention.