Sulfadimethoxine-Trimethoprim
Brands: Tribrissen, Bactrim
Sulfadimethoxine-Trimethoprim is a combination antibiotic for treating infections in pets.
Used for
- respiratory infections
- urinary infections
- gastrointestinal infections
How it is given
- Administration
- oral
- Frequency
- once daily
- Duration
- 5-14 days
- Storage
- store at room temperature, away from moisture and light
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- 12.5 mg/lb daily
dog
- Large dogs
- 12.5 mg/lb daily
- Small dogs
- 12.5 mg/lb daily
- Medium dogs
- 12.5 mg/lb daily
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- sulfadimethoxine
- trimethoprim
Side effects
Common
- vomiting
- diarrhea
Rare
- loss of appetite
Severe
- allergic reactions
Do not use when
- allergy to sulfonamides
- severe liver disease
Interacts with
- methotrexate
- warfarin
Warnings
- monitor for allergic reactions
- adjust dose in liver/kidney disease
Sulfadimethoxine-Trimethoprim questions
What should I do if I miss a dose?
Give it as soon as you remember unless it's close to the next dose.
Can this medication be used in pregnant pets?
Use with caution; consult your veterinarian.
What should I do in case of overdose?
Contact your veterinarian immediately.
Can this medication be used in other animals?
Primarily for dogs and cats; consult a veterinarian for others.
What are the signs of an allergic reaction?
Look for swelling, hives, or difficulty breathing and contact your veterinarian.
Full drug detail
Overview
Sulfadimethoxine-Trimethoprim is a combination antibiotic used to treat a variety of bacterial infections in animals. It combines the effects of sulfadimethoxine and trimethoprim to effectively target and eliminate bacteria.
How It Works
Sulfadimethoxine-Trimethoprim works by disrupting the production of folic acid in bacteria, essential for their growth and replication. Sulfadimethoxine inhibits bacterial synthesis of folate, while Trimethoprim prevents the reduction of dihydrofolate to tetrahydrofolate.
Uses & Indications
This medication is commonly prescribed for:
- Respiratory tract infections
- Urinary tract infections
- Gastrointestinal infections
- Skin infections
Dosage Guidelines
Dogs:
- Small Dogs: 12.5 mg/lb of body weight daily
- Medium Dogs: 12.5 mg/lb of body weight daily
- Large Dogs: 12.5 mg/lb of body weight daily
Cats:
- Standard: 12.5 mg/lb of body weight daily
Administration
The medication is administered orally and should be given with food to reduce gastrointestinal upset.
Frequency
Typically administered once daily.
Duration
Treatment usually lasts for 5-14 days, depending on the infection and response to treatment.
Side Effects
Common
- Vomiting
- Diarrhea
Rare
- Loss of appetite
Severe
- Allergic reactions such as swelling, hives, or difficulty breathing (seek immediate veterinary attention)
Precautions & Warnings
- Not recommended for pets with known allergies to sulfonamides.
- Use caution in pets with liver or kidney disease.
Drug Interactions
- Drug Interaction 1: Methotrexate
- Drug Interaction 2: Warfarin
Storage
Store at room temperature, away from moisture and light.
FAQ
- What should I do if I miss a dose? If you miss a dose, give it as soon as you remember. If it is close to the next dose, skip the missed dose.
- Can this medication be used in pregnant pets? Use with caution; consult your veterinarian.
- What should I do in case of overdose? Contact your veterinarian immediately.
- Can this medication be used in other animals? This medication is primarily for dogs and cats; consult your veterinarian for other animals.
- What are the signs of an allergic reaction? Look for swelling, hives, or difficulty breathing and contact your veterinarian.