Trimethoprim-sulfadiazine
Brands: Tribrissen, Bactrim
Trimethoprim-sulfadiazine is a broad-spectrum antibiotic used to treat bacterial infections in pets.
Used for
- urinary tract infections
- respiratory infections
- skin infections
How it is given
- Administration
- oral
- Frequency
- twice daily
- Duration
- typical treatment duration is 7-14 days
- Storage
- Store at room temperature, away from moisture and sunlight
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- 15 mg/kg twice daily
dog
- Large dogs
- 12.5 mg/kg twice daily
- Small dogs
- 12.5 mg/kg twice daily
- Medium dogs
- 12.5 mg/kg twice daily
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- Trimethoprim
- Sulfadiazine
Side effects
Common
- vomiting
- diarrhea
Rare
- allergic reactions
Severe
- blood dyscrasias
Do not use when
- sulfa allergies
- severe liver disease
Interacts with
- other antibiotics
- diuretics
Warnings
- Do not use in pregnant animals without vet advice
- Monitor for allergic reactions
Trimethoprim-sulfadiazine questions
What should I do if I miss a dose?
If you miss a dose, administer it as soon as you remember unless it's close to the next dose. Never double up.
Can pregnant pets take Trimethoprim-sulfadiazine?
Use with caution and always consult a veterinarian.
Is it safe for puppies and kittens?
Consult a veterinarian as younger animals may require adjusted dosages.
What if my pet has an allergic reaction?
Discontinue use immediately and contact your veterinarian.
Can this medication be used long-term?
Typically used short-term; long-term use should be monitored by a veterinarian.
Full drug detail
Overview
Trimethoprim-sulfadiazine is a combination antibiotic used to treat a variety of bacterial infections in pets. This medication is commonly prescribed for dogs, cats, and horses. It is important to consult with a veterinarian before administering this drug to ensure it is appropriate for your pet's condition.
How It Works
Trimethoprim and sulfadiazine work synergistically to inhibit bacterial growth by blocking the production of folic acid, a vital component for bacterial replication. Together, they provide a broad-spectrum bactericidal effect.
Uses & Indications
Trimethoprim-sulfadiazine is used to treat infections such as:
- Urinary tract infections
- Respiratory infections
- Skin infections
- Gastrointestinal infections
- Soft tissue infections
Dosage Guidelines
Dosage varies based on the animal's size and condition. Always follow a veterinarian's instructions.
For Dogs
- Small Dogs: 12.5 mg/kg twice daily
- Medium Dogs: 12.5 mg/kg twice daily
- Large Dogs: 12.5 mg/kg twice daily
For Cats
- Standard Dosage: 15 mg/kg twice daily
Administration
The drug is administered orally, usually in tablet form. Ensure your pet completes the full course even if symptoms improve.
Side Effects
Common
- Vomiting
- Diarrhea
- Loss of appetite
Rare
- Allergic reactions
Severe
- Blood dyscrasias (requires immediate veterinary attention)
Precautions & Warnings
- Do not use in animals with known sulfa allergies.
- Caution in pets with liver or kidney disease.
Drug Interactions
- May interact with other antibiotics and certain diuretics.
Storage
Store at room temperature, away from moisture and direct sunlight.
FAQ
What should I do if I miss a dose?
If you miss a dose, administer it as soon as you remember unless it's close to the next dose. Never double up.
Can pregnant pets take Trimethoprim-sulfadiazine?
Use with caution and always consult a veterinarian.
Is it safe for puppies and kittens?
Consult a veterinarian as younger animals may require adjusted dosages.
What if my pet has an allergic reaction?
Discontinue use immediately and contact your veterinarian.
Can this medication be used long-term?
Typically used short-term; long-term use should be monitored by a veterinarian.
Meta Title
Trimethoprim-sulfadiazine for Pets: Uses, Dosage & Side Effects
Meta Description
Learn about Trimethoprim-sulfadiazine, a broad-spectrum antibiotic for pets. Includes uses, dosage, side effects, and precautions. Consult your vet.