Yohimbine
Brands: Yobine, Antagonil
Yohimbine is used to reverse sedation in pets, primarily dogs and cats.
Used for
- Reversal of sedation
- Anesthesia recovery
How it is given
- Administration
- injection
- Frequency
- as needed
- Duration
- typically immediate effect after administration
- Storage
- Store in a cool, dry place away from light
- Pregnancy safety
- caution
Always confirm the exact dose with your veterinarian before giving any medicine.
Typical dose ranges
cat
- Standard
- 0.1 mg/kg
dog
- Large dogs
- 0.1 mg/kg
- Small dogs
- 0.1 mg/kg
- Medium dogs
- 0.1 mg/kg
Ranges are reference only. Your vet sets the dose for your pet's weight and condition.
Active ingredients
- Yohimbine Hydrochloride
Side effects
Common
- Increased heart rate
- Muscle tremors
Rare
- Vomiting
Severe
- Severe allergic reactions
Do not use when
- Known hypersensitivity
- Certain heart conditions
Interacts with
- Other adrenergic drugs
- CNS stimulants
Warnings
- Monitor heart rate
- Consult veterinarian
Yohimbine questions
What is Yohimbine used for?
Yohimbine is used to reverse sedation effects in pets, particularly dogs and cats.
Can Yohimbine be used for all animals?
Primarily used for dogs and cats; always consult a veterinarian.
How quickly does Yohimbine work?
Effects are usually seen within minutes of administration.
Are there any special precautions?
Yes, use cautiously in pets with cardiovascular issues.
Is a prescription required for Yohimbine?
Yes, it requires a veterinary prescription.
Full drug detail
Overview
Yohimbine is an alpha-2 adrenergic receptor antagonist primarily used in veterinary medicine to reverse the effects of sedation in animals, particularly in dogs and cats. It is most commonly used to counteract the effects of xylazine, a sedative.
How It Works
Yohimbine works by blocking the alpha-2 adrenergic receptors, which reverses the sedative effects of certain drugs like xylazine. This action helps restore normal central nervous system function and alertness in animals.
Uses & Indications
Yohimbine is primarily indicated for reversing sedation in pets, especially following the administration of sedatives like xylazine. It helps in recovery from anesthesia and sedation, allowing the pet to regain normal physiological functions.
Dosage Guidelines
Dogs
- Small Dogs: 0.1 mg/kg
- Medium Dogs: 0.1 mg/kg
- Large Dogs: 0.1 mg/kg
Cats
- Standard Dosage: 0.1 mg/kg
Administration
Yohimbine is administered through injection. The exact dosage and administration should always be determined by a veterinarian.
Frequency
Typically administered once when needed to reverse sedation.
Duration
Yohimbine is used for immediate reversal and is not typically used for extended periods.
Side Effects
Common
- Increased heart rate
- Muscle tremors
Rare
- Vomiting
Severe
- Severe allergic reactions requiring immediate veterinary attention
Precautions & Warnings
- Ensure the correct dosage is given to avoid adverse effects.
- Use with caution in animals with heart disease.
Drug Interactions
- Yohimbine may interact with other adrenergic drugs.
- Use cautiously with other CNS stimulants.
Storage
Store at room temperature away from moisture and light.
FAQ
- What is Yohimbine used for? Yohimbine is used to reverse sedation effects in pets, particularly dogs and cats.
- Can Yohimbine be used for all animals? Primarily used for dogs and cats; always consult a veterinarian.
- How quickly does Yohimbine work? Effects are usually seen within minutes of administration.
- Are there any special precautions? Yes, use cautiously in pets with cardiovascular issues.
- Is a prescription required for Yohimbine? Yes, it requires a veterinary prescription.
Contraindications
- Do not use in animals with known hypersensitivity to Yohimbine.
- Avoid in animals with certain heart conditions.
Interactions
- Interaction with other adrenergic drugs.
Warnings
- Important Warning: Monitor heart rate and blood pressure after administration.
- Important Warning: Always consult a veterinarian before use.
Storage
Store in a cool, dry place away from direct sunlight.